he-bin tang professor
email:
team website:
tel: 86-27-67842332
ucurriculum vitae
•hunancollege of traditional chinese medicine, b.m., 1996
•zhuzhou traumatological hospital of traditional chinese medicine, hunan, ent doctor, 1996-1998
•hiroshimauniversity, hiroshima, japan, m.s., 2002
•hiroshimauniversity, hiroshima, japan, ph.d., 2005
•hiroshimauniversity, hiroshima, japan, assistant professor, 2005-2009
•south-centraluniversity for nationalities, professor, since 2009
uresearch interests
•pharmacological research on early warning and precise medication of gradual progression from fatty liver disease to liver cancer.
•pharmacological research on anti-liver cancer activity of traditional chinese medicine.
•mechanism of chronic pain
uassociation and awards
•clinical research branch of china information association for tradtional chinese medicine and pharmacy, standing director;
•chinese medicine experimental pharmacology branch of china association for chinese medicine, director
•the hubei pharmacological society, director;
urepresentative publications (*corresponding author)
1.2. chen mt, yang yj, li ys, li xj, zhang wk, wang jp, wang x, tian gh, tang hb*. shengfu oil enhances the healing of full-thickness scalded skin accompanying the differential regulation of β-catenin, dlk1, and cox-2. frontiers in pharmacology. 2017, 8: 801. doi: 10.3389/fphar.2017.00801.
2.ning d, zhang wk, tian h, li xj, liu m, li ys*, tang hb. the involvement of β-catenin/cox-2/vegf axis in nmda-caused retinopathy. journal of ophthalmology. 2017; 2017: 9760501. doi: 10.1155/2017/9760501.
3.li xj, mu ym, qin qf, zeng zx, li ys, zhang wk, tang hb*, tian gh, shang hc. chronic high-dosage fish oil exacerbates gut-liver axis injury in alcoholic steatohepatitis in mice: the roles of endotoxin and il-4 in kupffer cell polarization imbalance. toxicology research. 2017, 6, 611-620.doi: 10.1039/c7tx00037e
4.zhang wk, gu hw, li xj, li ys, tang hb*, tian gh, shang hc.the dark side of the force - lipid nanoparticles enhance the oncogenesis of diethylnitrosamine and result in liver cancer in mice. nanomedicine: nanotechnology, biology, and medicine. 2017, 13(2): 701-711. doi: 10.1016/j.nano.2016.09.017.
5.zhang wk, tao ss, li tt, li ys, li xj, tang hb*, cong rh, ma fl, wan cj. nutmeg oil alleviates chronic inflammatory pain through inhibition of cox-2 expression and substance p release in vivo. food & nutrition research. 2016, 60: 30849.
6.tian gh, tao ss, chen mt, li ys, li yp, shang hc, tang xy, chen jx, tang hb*. electroacupuncture treatment alleviates central poststroke pain by inhibiting brain neuronal apoptosis and aberrant astrocyte activation. neural plasticity. 2016, 2016: 1437148.
7.li ys, leng cl, chen mt, zhang wk, li xj, tang hb*, shang hc, zhu lh. mouse hepatic neoplasm formation induced by trace level and low frequency exposure to diethylnitrosamine through β-catenin signaling pathway. toxicology research. 2016, 5:210-223.
8.li xj, yang yj, li tt, li ys, zhang wk, tang hb*. α-pinene, linalool, and 1-octanol contribute to the topical anti-inflammatory and analgesic activities of frankincense by inhibiting cox-2. journal of ethnopharmacology. 2016, 179:22-26.
9.li xj, mu ym, li tt, yang yl, zhang mt, li ys, zhang wk, tang hb*, shang hc. gynura procumbens reverses acute and chronic ethanol-induced liver steatosis through mapk/srebp-1c-dependent and -independent pathways. journal of agricultural and food chemistry. 2015, 63(38):8460-8471.
10.li ys, xi y, li xj, leng cl, jia mm, zhang wk, tang hb*. up-regulation of the biosynthesis and release of substance p through wnt/β-catenin signaling pathway in rat dorsal root ganglion cells. plos one. 2015, 10(6): e0129701.
11.li ys, chen bf, li xj, zhang wk, tang hb*. cytotoxicity of polyaniline nanomaterial on rat celiac macrophages in vitro. plos one. 2014, 9(9):e107361
12.li xj, jia mm, li ys*, yang yl, mao xq, tang hb. involvement of substance p/neurokinin-1 receptor in the analgesic and anticancer activities of minimally toxic fraction from the traditional chinese medicine liu-shen-wan in vitro. biological and pharmaceutical bulletin. 2014, 37(3):431-438.
13.li l, guo ql, li j, yan w, leng cl, tang hb*, lu qw, tang be. design of a polymer ligand for the one-step preparation of highly stable fluorescent ag5 clusters for tissue labeling. journal of materials chemistry b. 2013, 1, 3999-4004.
14.li ys, wang jx, jia mm, liu m, li xj, tang hb*. dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance p in rats. journal of pharmacological sciences. 2012,118: 43-54.
15.li ys, liu m, nakata y, tang hb*. β-catenin accumulation in nuclei of hepatocellular carcinoma cells up-regulates glutathione-s-transferase m3 mrna.world journal of gastroenterology, 2011, 17:1772.
urepresentative grants
•grant from national natural science foundation of china: protective mechanisms of gynura procumbens against liver cancer through the inhibition of inflammatory feedback loop of“β-catenin/cox-2, no. 81673711, 2016;
•grant from national natural science foundation of china: a study on dai medicine pabengban alleviating alcoholic live disease by activating ampk in the gut-liver axies, no. 81403188, 2014;
•grant from national natural science foundation of china: modulation mechanism of shengfu oil on scarless healing in full-thickness burn wounds, no. 81373842, 2013;
•grant from national natural science foundation of china: the regulatory role of wnt/β-catenin signaling pathway in the development of primary hepatocellular carcinoma, no. 81101538, 2011;
•grant from national natural science foundation of china: the role of non-neuronal cells in the regulation of substance p release from dorsal root ganglion neurons, no. 81070887, 2010;
•grant-in-aid for scientific research (b) from the japan society for the promotion of science: molecular mechanism of peptide neurotransmitter release from primary afferent neurons, no. 19790189, 2007.
