name: guangwen shu
discipline: chinese medicine
research direction:
active substances and mechanism of traditional drugs in the treatment of liver diseases
email: shuguangwen@whu.edu.cn
experience:
2002/09-2006/06, school of life sciences, wuhan university, bachelor.
2006/09-2011/06, institute of biochemistry and cell biology, shanghai institute of life sciences, chinese academy of sciences, doctor.
since 2011/07, school of pharmaceutical sciences, central-south university for nationalities, faculty.
selected publications:
1. chlorogenic acid methyl ester exerts strong anti-inflammatory effects via inhibiting the cox-2/nlrp3/nf-κb pathway. food funct. 2018 dec 13; 9(12): 6155-6164.
2. activity of isoliensinine in improving the symptoms of type 2 diabetic mice via activation of amp-activated kinase and regulation of pparγ. j agric food chem. 2017 aug 23; 65(33): 7168-7178.
3. amplexicaule a exerts anti-tumor effects by inducing apoptosis in human breast cancer. oncotarget. 2016 apr 5; 7(14): 18521-30.
4. antidiabetic effects of flavonoids from sophora flavescens etoac extract in type 2 diabetic kk-ay mice. j ethnopharmacol. 2015 aug 2; 171: 161-70.
5. chemical composition of total flavonoids from polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: potential roles of suppressing stat3 signaling. food chem toxicol. 2015 jun; 80: 62-71.
